Our ChimerAds technology has proven very efficient in isolating high quality lactoferrin from both milk and whey

Cute happy asian baby girl with milk bottle

Production of lactoferrin

Bovine lactoferrin (bLf) is commercially available, but the quality varies greatly among manufacturers. The current industry practice is to isolate lactoferrin from milk or whey by ion-exchange chromatography followed by membrane filtration. This process is not necessarily able to effectively remove other minor components and endotoxins, and more steps may be needed (Perraudin & De Valck, 2020).

However, Lihme Protein Solutions has developed a solution where highly specific adsorbent, combined with our ChimerAds technology, isolates a very pure lactoferrin in few steps.

Health benefits
of lactoferrin

Due to its multifunctional character and great resemblance to its human counterpart, bovine lactoferrin has a significant commercial appeal, not only in infant formulas but also for maintaining human health. 

The health benefits of lactoferrin includes immunomodulating properties, antibacterial, antiviral, and antifungal activities, anti-inflammatory activities, and iron regulation.

Applications of lactoferrin in the treatment of human diseases and other industries (Cao et al.2023,

Lactoferrin - the protein

Lactoferrin is an 80-kDa iron-binding glycoprotein that belongs to the transferrin family. This multifunctional protein is found in secretions of mammals, most abundant in human colostrum (~7 g/L) and mature human milk (~1 g/L) and to a lesser content in bovine colostrum (~1.5 mg/L) and mature bovine milk (~0.5 mg/L).

The function of lactoferrin is due to its ability to sequester iron and to interfere with cellular receptors of pathogenic microorganisms.

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